Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380946 | 0.77 | IP6K1 (0.53) | IP6K1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28190057 | 0.77 | LMNA (0.53) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL19169418 | 0.76 | PDE10A (0.60) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL11549916 | 0.74 | ALDH1A1 (0.57) | IP6K1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28484119 | 0.73 | ALDH1A1 (0.47) | IP6K1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL422358 | 0.72 | PDE10A (0.61) | MEN1KMT2AALDH1A1NPC1PDE10A | |
| SCHEMBL20269925 | 0.72 | ALDH1A1 (0.52) | IP6K1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21390765 | 0.72 | ALDH1A1 (0.52) | IP6K1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26858214 | 0.72 | KMT2A (0.56) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL21390628 | 0.71 | IP6K1 (0.44) | IP6K1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621276-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |