Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8328819 | 0.99 | KMT2A (0.34) | KMT2ALMNAGAAMAPTRECQL | |
| SCHEMBL9380965 | 0.75 | CTSD (0.36) | KMT2ALMNAGAAMAPTRECQL | |
| Hydrochloric Acid SCHEMBL8328815 | 0.74 | CTSD (0.35) | KMT2ALMNAGAAMAPTRECQL | |
| Bromide SCHEMBL8327518 | 0.73 | MEN1 (0.38) | KMT2ALMNAGAAMAPTRECQL | |
| SCHEMBL8324929 | 0.72 | KMT2A (0.41) | KMT2ALMNAGAAMAPTRECQL | |
| Bromide SCHEMBL8329364 | 0.67 | KDM4E (0.37) | MAPTRAB9AL3MBTL1 | |
| SCHEMBL8327415 | 0.65 | POLB (0.39) | KMT2ALMNAGAAMAPTRECQL | |
| Hydrochloric Acid SCHEMBL8329391 | 0.62 | RXFP1 (0.40) | KMT2ALMNAGAAMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8328344 | 0.61 | KMT2A (0.39) | KMT2ALMNAGAAMAPTRAB9A | |
| SCHEMBL8324947 | 0.60 | CTSD (0.43) | KMT2ALMNACTSDGUSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580616-A1 | NEW ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992017477-A1 | NEW ACTIVE COMPOUNDS | AKTIEBOLAGET ASTRA (SE) | 1992-10-15 | — | — | WO | disclosed |