Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | HTR2A | P28223 | 7/20 | 0.58 |
| ▸ | DRD3 | P35462 | 6/20 | 0.58 |
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 2/20 | 0.55 |
| ▸ | ATP4B | P51164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694676 | 0.80 | DRD2 (0.63) | DRD2HTR2ADRD3HTR1ASLC6A4 | |
| SCHEMBL30964246 | 0.78 | DRD2 (0.57) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7963191 | 0.78 | RAB9A (0.81) | DRD2HTR2ADRD3HTR1ASLC6A4 | |
| SCHEMBL15941384 | 0.78 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL7534676 | 0.78 | RAB9A (0.67) | DRD2DRD3HTR1AHTR7RAB9A | |
| SCHEMBL30964251 | 0.77 | DRD2 (0.68) | DRD2DRD3DRD4 | |
| SCHEMBL31694684 | 0.77 | DRD2 (0.61) | DRD2HTR2ADRD3HTR1ASLC6A4 | |
| SCHEMBL14144180 | 0.77 | PPARD (0.62) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL23965748 | 0.77 | RAB9A (0.69) | RAB9ANPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL9589873 | 0.76 | PPARG (0.49) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398425-B1 | Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA NV (BE) | 1994-03-16 | — | — | EP | disclosed |