Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190716 | 0.82 | GBA1 (0.75) | GBA1RORCFUCA1S1PR1S1PR5 | |
| SCHEMBL14759418 | 0.82 | GBA1 (0.75) | GBA1RORCFUCA1S1PR1S1PR5 | |
| SCHEMBL742926 | 0.82 | GBA1 (0.75) | GBA1RORCFUCA1S1PR1S1PR5 | |
| SCHEMBL14759416 | 0.82 | GBA1 (0.75) | GBA1RORCFUCA1S1PR1S1PR5 | |
| SCHEMBL24759877 | 0.81 | GBA1 (0.50) | GBA1ALDH1A1TSHRKDM4ES1PR5 | |
| SCHEMBL12303419 | 0.79 | RORC (0.64) | RORCFUCA1GRIN2BKDM4ES1PR1 | |
| SCHEMBL8089289 | 0.79 | RORC (0.64) | RORCFUCA1GRIN2BKDM4ES1PR1 | |
| SCHEMBL8089286 | 0.79 | RORC (0.64) | RORCFUCA1GRIN2BKDM4ES1PR1 | |
| SCHEMBL12303418 | 0.79 | RORC (0.64) | RORCFUCA1GRIN2BKDM4ES1PR1 | |
| SCHEMBL4094892 | 0.78 | GBA1 (0.65) | GBA1FUCA1S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394991-B1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |