Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | RORC | P51449 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586982 | 0.90 | RORC (0.67) | LMNARORCMAPK1HTTGAA | |
| SCHEMBL6589148 | 0.86 | RORC (0.56) | LMNARORCMAPK1HTTGAA | |
| SCHEMBL9383327 | 0.84 | RORC (0.61) | LMNARORCMAPK1GAANPSR1 | |
| SCHEMBL333115 | 0.82 | RECQL (0.65) | LMNARORCMAPK1GAASMN1; SMN2 | |
| SCHEMBL16922179 | 0.82 | RECQL (0.65) | LMNARORCMAPK1GAASMN1; SMN2 | |
| SCHEMBL29733671 | 0.82 | RECQL (0.65) | LMNARORCMAPK1GAASMN1; SMN2 | |
| SCHEMBL7974517 | 0.82 | RORC (0.52) | LMNARORCMAPK1HTTGAA | |
| SCHEMBL2855075 | 0.81 | MAPK1 (0.59) | LMNARORCMAPK1HTTGAA | |
| SCHEMBL9383696 | 0.81 | RORC (0.56) | LMNARORCMAPK1HTTGAA | |
| SCHEMBL10711606 | 0.80 | LMNA (0.57) | LMNAGAASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |