SCHEMBL9384995

SCHEMBL9384995

CC(O)C1C(=O)N([Si](C)(C)C(C)(C)C)C1SC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11180312 0.87 KIF11 (0.30)
SCHEMBL11033057 0.87
SCHEMBL11032875 0.87 FAAH (0.33)
SCHEMBL10540916 0.86 ELANE (0.33)
SCHEMBL10758658 0.85
SCHEMBL10758175 0.85
SCHEMBL11033113 0.85
SCHEMBL10973636 0.85 KIF11 (0.33)
SCHEMBL11031327 0.84
SCHEMBL11128519 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994003168-A1 5 S PENEM DERIVATIVES, THEIR PREPARATION AND USE SMITHKLINE BEECHAM PLC (GB) 1994-02-17 WO disclosed
US-4461727-A PENICILLINS BRISTOL-MYERS COMPANY (US) 1984-07-24 US disclosed
US-4406834-A ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1983-09-27 US disclosed
US-4378314-A FOR PENICILLINS AND CEPHALOSPORINS BRISTOL MYERS COMPANY (US) 1983-03-29 US disclosed
US-4374065-A PENICILLINS, ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1983-02-15 US disclosed
US-4282150-A CHEMICAL INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1981-08-04 US disclosed
US-4272437-A PENICILLINS BRISTOL-MYERS COMPANY (US) 1981-06-09 US disclosed