Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385023 | 0.83 | L3MBTL1 (0.53) | L3MBTL1NR3C1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9384803 | 0.83 | L3MBTL1 (0.50) | L3MBTL1NR3C1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9385041 | 0.79 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6121494 | 0.76 | ALDH1A1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6192249 | 0.74 | KMT2A (0.47) | L3MBTL1NR3C1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7110837 | 0.74 | L3MBTL1 (0.57) | L3MBTL1NR3C1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL12513035 | 0.72 | L3MBTL1 (0.61) | L3MBTL1NR3C1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7107174 | 0.71 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12808838 | 0.70 | ALDH1A1 (0.60) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL28458116 | 0.69 | ESR1 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |