Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157289 | 0.78 | L3MBTL1 (0.38) | KDM4EALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL5604157 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3828353 | 0.71 | NPC1 (0.35) | NOS2KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8583255 | 0.67 | CDC25A (0.35) | ALDH1A1 | |
| SCHEMBL8829283 | 0.64 | GRM5 (0.32) | GRM5PDE10AKDM4EALDH1A1GAA | |
| SCHEMBL10527 | 0.62 | — | — | |
| SCHEMBL29583126 | 0.62 | — | — | |
| SCHEMBL5602057 | 0.61 | KCNH2 (0.39) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL11564094 | 0.60 | HRH1 (0.59) | KDM4EALDH1A1LMNATSHRHRH3 | |
| Bromide SCHEMBL14801933 | 0.60 | HRH1 (0.59) | KDM4EALDH1A1LMNATSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620813-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |