Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604157 | 0.74 | KDM4E (0.33) | ELANEALDH1A1 | |
| SCHEMBL18456446 | 0.69 | CDC25B (0.46) | CDC25ACDC25BPTPN1DRD3NR1H2 | |
| SCHEMBL27942011 | 0.68 | CDC25B (0.49) | CDC25ACDC25BPTPN1DRD3NR1H2 | |
| SCHEMBL10607496 | 0.67 | PTPN1 (0.41) | CDC25ACDC25BPTPN1DRD3NR1H2 | |
| SCHEMBL9385170 | 0.67 | NOS2 (0.33) | ALDH1A1 | |
| SCHEMBL2785045 | 0.64 | TLR8 (0.33) | IDO1 | |
| SCHEMBL5602057 | 0.63 | KCNH2 (0.39) | PTPN1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL27744901 | 0.63 | PTPN1 (0.53) | CDC25ACDC25BPTPN1NR1H2NR1H3 | |
| SCHEMBL5531153 | 0.63 | ELANE (0.41) | NR1H2NR1H3ELANEALDH1A1 | |
| SCHEMBL2872377 | 0.63 | CNR1 (0.35) | CDC25ACDC25BPTPN1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741794-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-04-21 | — | — | US | disclosed |
| EP-0620813-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |