Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9383323 | 0.99 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9385253 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9383816 | 0.87 | KDM4E (0.47) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9383329 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9385887 | 0.86 | KDM4E (0.46) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9388613 | 0.85 | CYP2C19 (0.59) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9428349 | 0.84 | MEN1 (0.41) | ALDH1A1CYP2C19MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL9384149 | 0.84 | CYP2C19 (0.58) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9385661 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9389262 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |