Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9383329 | 0.99 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9383816 | 0.89 | KDM4E (0.47) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9385887 | 0.88 | KDM4E (0.46) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9388613 | 0.88 | CYP2C19 (0.59) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9385247 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9384149 | 0.87 | CYP2C19 (0.58) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9385661 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9383323 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL9389262 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| Oxalic Acid SCHEMBL9388811 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |