Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388443 | 0.90 | MAPT (0.67) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL5153567 | 0.89 | MAPT (0.63) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL9003269 | 0.87 | MAPT (0.70) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| Diethylamine SCHEMBL28410463 | 0.86 | MAPT (0.89) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL10489391 | 0.84 | MAPT (0.72) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL570831 | 0.83 | MAPT (1.00) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL1405413 | 0.82 | MAPT (0.96) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| Bromide SCHEMBL28010281 | 0.82 | MAPT (0.96) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL195897 | 0.81 | MAPT (0.55) | MAPTALDH1A1GLASMN1; SMN2MEN1 | |
| SCHEMBL14368589 | 0.81 | MAPT (0.59) | MAPTALDH1A1GLASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |