Bromide

Bromide

SCHEMBL28010281

Br.CCNc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.48
MAPT P10636 4/20 0.96
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 2/20 0.59
RECQL P46063 1/20 0.59
POLB P06746 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.53
GLA P06280 1/20 0.53
PTPRF P10586 1/20 0.51
PTPN2 P17706 1/20 0.51
PTPN1 P18031 1/20 0.51
PTPN11 Q06124 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HPGD P15428 1/20 0.50
ALOX12 P18054 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.49
RAB9A P51151 1/20 0.49
IDO1 P14902 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570831 0.98 MAPT (1.00) MAPTALDH1A1HSD17B10RECQLPOLB
Hydrochloric Acid SCHEMBL1405413 0.96 MAPT (0.96) MAPTALDH1A1HSD17B10RECQLPOLB
Diethylamine SCHEMBL28410463 0.92 MAPT (0.89) MAPTALDH1A1HSD17B10RECQLPOLB
SCHEMBL9243455 0.92 MAPT (0.89) MAPTALDH1A1HSD17B10RECQLPOLB
SCHEMBL14713993 0.88 MAPT (0.80) MAPTALDH1A1HSD17B10RECQLPOLB
SCHEMBL14537303 0.88 MAPT (0.80) MAPTALDH1A1HSD17B10RECQLPOLB
Pyridine SCHEMBL20534855 0.85 MAPT (0.75) MAPTALDH1A1HSD17B10RECQLPOLB
SCHEMBL10489391 0.82 MAPT (0.72) MAPTALDH1A1HSD17B10RECQLSMN1; SMN2
SCHEMBL9385249 0.82 MAPT (0.71) MAPTALDH1A1HSD17B10RECQLPOLB
SCHEMBL4955548 0.81 MAPT (0.70) MAPTALDH1A1HSD17B10RECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119110659-A Method for preparing quasi-two-dimensional perovskite film by stripping and application thereof 五邑大学 2024-12-10 CN claimed
CN-119110659-A Method for preparing quasi-two-dimensional perovskite film by stripping and application thereof 五邑大学 2024-12-10 CN disclosed
CN-107759477-A A kind of preparation method of p-nitrophenyl ethylamine hydrochloride 阿里化学(常州)有限公司 2018-03-06 CN disclosed
CN-104557566-A Preparation method for 4-nitrobenzene ethylamine hydrobromide ANHUI DEXINJIA BIOPHARM CO LTD 2015-04-29 CN disclosed
CN-104557566-A Preparation method for 4-nitrobenzene ethylamine hydrobromide ANHUI DEXINJIA BIOPHARM CO LTD 2015-04-29 CN disclosed