Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327315 | 0.84 | SLC6A2 (0.50) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL4975215 | 0.82 | KMT2A (0.45) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL85414 | 0.80 | KMT2A (0.48) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL13437398 | 0.79 | KMT2A (0.50) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL9381748 | 0.78 | HTR2A (0.54) | KMT2ATDP1L3MBTL1LMNACYP1A2 | |
| SCHEMBL9380040 | 0.78 | MAOA (0.47) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL9384519 | 0.77 | HRH3 (0.47) | KMT2ATDP1L3MBTL1KCNH2HRH3 | |
| SCHEMBL9369305 | 0.76 | KMT2A (0.52) | KMT2ATDP1L3MBTL1CA12CA1 | |
| SCHEMBL15645221 | 0.74 | LTA4H (0.65) | LTA4HHRH3 | |
| SCHEMBL15645223 | 0.74 | LTA4H (0.65) | LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398426-B1 | Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA NV (BE) | 1994-03-09 | — | — | EP | disclosed |
| US-5070090-A | SUSTAINED RELEASE FROM CYCLODEXTRIN INCLUSION COMPOUND | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-12-03 | — | — | US | disclosed |
| EP-0398426-A1 | Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-22 | — | — | EP | disclosed |