Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462665 | 0.85 | HDAC3 (0.55) | HDAC1PIN1CCKBRMEN1KMT2A | |
| SCHEMBL9389507 | 0.84 | KMT2A (0.44) | HDAC1PIN1HTTMAPTMEN1 | |
| SCHEMBL9388771 | 0.84 | PADI4 (0.49) | HDAC1MAPT | |
| SCHEMBL9385513 | 0.84 | KMT2A (0.51) | HDAC1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9388240 | 0.82 | SMN1; SMN2 (0.50) | HDAC1HTTKDM4EMEN1KMT2A | |
| SCHEMBL9385748 | 0.82 | NPC1 (0.53) | HDAC1HTTKDM4EMEN1KMT2A | |
| SCHEMBL9389538 | 0.82 | NPC1 (0.58) | HDAC1HTTKDM4EMEN1KMT2A | |
| SCHEMBL9385616 | 0.82 | HPGD (0.44) | HDAC1HTTKDM4EMAPTMEN1 | |
| SCHEMBL9387960 | 0.82 | CTSL (0.48) | HDAC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9384648 | 0.82 | METAP2 (0.51) | METAP2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007815-A2 | SMALL PEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1994-04-14 | — | — | WO | claimed |