Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855948 | 0.86 | CA12 (0.61) | CA2CA12CA1CA7CA9 | |
| SCHEMBL4261690 | 0.85 | MAPK1 (0.47) | CA9HTTRAB9ALMNAMAPK1 | |
| SCHEMBL8128858 | 0.85 | HTT (0.54) | CA2CA12CA1CA7CA9 | |
| SCHEMBL22394732 | 0.85 | CDC25B (0.54) | CA2CA12CA1CA7CA9 | |
| SCHEMBL201405 | 0.83 | LMNA (0.53) | CA2CA12CA1CA7CA9 | |
| SCHEMBL29792549 | 0.83 | LMNA (0.53) | CA2CA12CA1CA7CA9 | |
| SCHEMBL7482250 | 0.81 | MAPT (0.51) | CA2CA12CA1CA7CA9 | |
| SCHEMBL1495317 | 0.81 | CA12 (0.50) | CA2CA12CA1CA7CA9 | |
| SCHEMBL30803094 | 0.81 | CA2 (0.53) | CA2CA12CA1CA7CA9 | |
| SCHEMBL8130669 | 0.80 | MRGPRX4 (0.55) | CA2CA12CA1CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409484-B1 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5071863-A | Antiallergens; antiinflammatory agents; enzyme inhibitors | PFIZER INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0409484-A2 | 4,5,6,7-Tetrasubstituted benzoxazolones | PFIZER INC. (US) | 1991-01-23 | — | — | EP | disclosed |