Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816132 | 0.79 | SRC (0.59) | SRCHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL5892 | 0.76 | HTT (0.44) | SRCHTTKMT2AMEN1TDP1 | |
| SCHEMBL2309806 | 0.75 | MEN1 (0.48) | SRCHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL8530739 | 0.75 | MEN1 (0.48) | SRCHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL10912623 | 0.75 | HTT (0.41) | SRCHTTKMT2AMEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL27627985 | 0.73 | MEN1 (0.46) | SRCHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL30337036 | 0.71 | SRC (0.53) | SRCHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL27651298 | 0.70 | HTT (0.48) | HTTKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL7526246 | 0.70 | HTT (0.48) | HTTKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL8370301 | 0.69 | HTT (0.59) | SRCHTTKMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335409-B1 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4969949-A | NONPHYTOTOXIC | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| EP-0335409-A2 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |