Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443636 | 0.76 | CA1 (0.48) | CA1CA2SIGMAR1CYP19A1NPC1 | |
| SCHEMBL9390589 | 0.74 | KCNA3 (0.62) | XDHSIGMAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL9390412 | 0.73 | PTAFR (0.60) | CYP19A1KDM4EALDH1A1 | |
| SCHEMBL20576216 | 0.72 | CA1 (0.51) | CA1CA2LMNAKDM4EALDH1A1 | |
| SCHEMBL3277184 | 0.69 | CA1 (0.51) | CA1CA2CYP19A1LMNAKDM4E | |
| SCHEMBL9346869 | 0.69 | ALDH1A1 (0.60) | DRD3DRD2SIGMAR1NPC1RAB9A | |
| SCHEMBL9390564 | 0.69 | KCNA3 (0.52) | XDHSIGMAR1KDM4EALDH1A1HRH3 | |
| SCHEMBL3268493 | 0.68 | CA1 (0.59) | CA1CA2CYP19A1NPC1RAB9A | |
| SCHEMBL3833769 | 0.67 | CYP19A1 (0.77) | CA1CA2CYP19A1NPC1RAB9A | |
| SCHEMBL9391141 | 0.67 | SIGMAR1 (0.51) | XDHSIGMAR1KDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001434-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AS PAF ANTAGONISTS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1994-01-20 | — | — | WO | disclosed |