Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.86 |
| ▸ | MAOA | P21397 | 3/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.86 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
| ▸ | TSHR | P16473 | 1/20 | 0.86 |
| ▸ | ACHE | P22303 | 1/20 | 0.86 |
| ▸ | PDE4A | P27815 | 1/20 | 0.86 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.86 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxsalen SCHEMBL2302069 | 0.93 | CYP3A4 (1.00) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL29376525 | 0.93 | CYP3A4 (1.00) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL19168 | 0.93 | CYP3A4 (1.00) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL6142553 | 0.91 | CYP3A4 (0.97) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL10572509 | 0.85 | CYP3A4 (0.84) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL598765 | 0.84 | CYP3A4 (0.82) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Methoxsalen SCHEMBL11576767 | 0.83 | CYP3A4 (0.66) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| SCHEMBL9387172 | 0.80 | MAOA (0.64) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Bergapten SCHEMBL9792363 | 0.80 | CYP3A4 (0.74) | CYP3A4MAOACYP1A2CYP2A6MAPK1 | |
| Anthralin SCHEMBL17627910 | 0.78 | CYP3A4 (0.66) | CYP3A4MAOACYP1A2CYP2A6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009775-A1 | NOVEL FURO-COUMARINSULFONAMIDES AS PROTEIN KINASE C INHIBITORS | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-05-11 | — | — | WO | disclosed |
| US-5216014-A | Used for diagnosis and treatment of inflammatory, cardiovascular and neoplastic diseses | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |