Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.55 |
| ▸ | DDO | Q99489 | 5/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389032 | 0.89 | DAO (0.48) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389409 | 0.79 | DAO (0.68) | DAODDO | |
| SCHEMBL9393070 | 0.79 | DAO (0.63) | DAODDO | |
| SCHEMBL7352458 | 0.79 | DAO (0.53) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9393239 | 0.76 | DAO (0.48) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389293 | 0.76 | DAO (0.48) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9392765 | 0.75 | SRC (0.44) | DAODDOSRC | |
| SCHEMBL9387925 | 0.75 | DAO (0.53) | DAODDOSRC | |
| SCHEMBL9388969 | 0.75 | DAO (0.41) | DAODDOSRC | |
| SCHEMBL9389308 | 0.73 | DAO (0.56) | DAODDOGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |