SCHEMBL9392765

SCHEMBL9392765

O=c1[nH]c2cc(I)c(I)cc2c(=O)cc1O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.44
DAO P14920 10/20 0.42
DDO Q99489 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9387925 0.81 DAO (0.53) SRCDAODDO
SCHEMBL7352458 0.78 DAO (0.53) SRCDAODDO
SCHEMBL9387604 0.75 DAO (0.55) SRCDAODDO
SCHEMBL9388969 0.74 DAO (0.41) SRCDAODDO
SCHEMBL9389842 0.73 DAO (0.47) SRCDAODDO
SCHEMBL9390031 0.73 GRIN2D (0.58)
SCHEMBL9389319 0.73 GRIN2D (0.56) DAODDO
SCHEMBL2639080 0.72 DAO (0.61) DAODDO
SCHEMBL9007832 0.71 DAO (0.65) DAODDO
SCHEMBL9387632 0.71 DAO (0.65) DAODDO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994007500-A1 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS WEBER ECKARD (US) 1994-04-14 WO disclosed