Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.68 |
| ▸ | DDO | Q99489 | 3/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389933 | 0.88 | DAO (0.52) | DAODDOCTSVCTSLPTGES | |
| SCHEMBL9393070 | 0.88 | DAO (0.63) | DAODDOKIF11CTSVCTSL | |
| SCHEMBL16767852 | 0.81 | DAO (1.00) | DAODDOTRPA1 | |
| SCHEMBL19032120 | 0.79 | LMNA (0.60) | DAOKIF11CTSVCTSL | |
| SCHEMBL9387604 | 0.79 | DAO (0.55) | DAODDO | |
| SCHEMBL9387738 | 0.79 | DAO (0.65) | DAODDOKIF11 | |
| SCHEMBL13267221 | 0.78 | KDM4E (0.54) | DAOKIF11CDK1CDK2TRPA1 | |
| SCHEMBL9452268 | 0.77 | KDM4E (0.61) | KIF11CYP2C9 | |
| SCHEMBL9389308 | 0.76 | DAO (0.56) | DAODDO | |
| SCHEMBL9393210 | 0.76 | DAO (0.49) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |