Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598758 | 0.87 | MAPT (0.50) | POLBMAPTMEN1KMT2AKDM4E | |
| SCHEMBL4543934 | 0.80 | BRD4 (0.50) | MAPTKDM4EHRH4KDM4CKEAP1 | |
| SCHEMBL6582983 | 0.78 | BRD4 (0.49) | ALDH1A1MAPTKDM4EHSD17B10KDM4C | |
| SCHEMBL9686105 | 0.76 | BRD4 (0.50) | ALDH1A1MAPTKDM4EHRH4KDM4C | |
| SCHEMBL3599361 | 0.75 | MAPT (0.50) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL1709827 | 0.70 | BRD4 (0.59) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1082894 | 0.70 | MAPK1 (0.51) | ALDH1A1POLBMAPTGAAPARP1 | |
| SCHEMBL3598756 | 0.70 | MAPK1 (0.43) | ALDH1A1POLBMEN1KMT2AALOX15 | |
| SCHEMBL1286631 | 0.69 | CA12 (0.54) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1082682 | 0.69 | MAPK1 (0.53) | ALDH1A1MAPTPARP1MAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304087-B1 | Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent | WARNER LAMBERT CO (US) | 1994-03-30 | — | — | EP | disclosed |
| US-4851418-A | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent | WARNER-LAMBERT COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0304087-A2 | Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent | WARNER-LAMBERT COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |