Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543934 | 0.97 | BRD4 (0.50) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL6582983 | 0.95 | BRD4 (0.49) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL3459225 | 0.87 | HRH4 (0.51) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL31149055 | 0.87 | HRH4 (0.51) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL13801290 | 0.84 | BRD4 (0.45) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL14410195 | 0.82 | BRD4 (0.46) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL30041257 | 0.80 | HRH4 (0.63) | HRH3HRH4 | |
| Trifluoroacetic Acid SCHEMBL30355123 | 0.77 | HRH4 (0.48) | DAODDOKDRHRH3HRH4 | |
| SCHEMBL20547348 | 0.76 | BRD4 (0.46) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL9387635 | 0.76 | ALDH1A1 (0.45) | HRH4KDM4EMAPTKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514268-A1 | Substituted amino acid azetidinyl pyridone derivatives, their preparation and use as medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-11-19 | — | — | EP | claimed |
| EP-0514268-A1 | Substituted amino acid azetidinyl pyridone derivatives, their preparation and use as medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-11-19 | — | — | EP | disclosed |