SCHEMBL1286631

SCHEMBL1286631

Nc1ccc2ccc(=O)[nH]c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA9 Q16790 2/20 0.54
CA1 P00915 1/20 0.54
CA3 P07451 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA13 Q8N1Q1 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
AR P10275 2/20 0.47
MAPKAPK2 P49137 1/20 0.47
RPS6KA3 P51812 1/20 0.47
CSNK2A1 P68400 1/20 0.47
PLK3 Q9H4B4 1/20 0.47
F11 P03951 1/20 0.47
MAPK1 P28482 2/20 0.46
PARP1 P09874 2/20 0.46
MEN1 O00255 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771379 0.85 CA12 (0.60) CA12CA9CA1CA3CA4
SCHEMBL5460543 0.79 TNKS2 (0.65) CA12CA9CA1CA3CA4
SCHEMBL17951770 0.77 MAPK1 (0.68) CA12CA9CA1CA3CA4
SCHEMBL30176791 0.74 CA12 (0.54) CA12CA9CA1CA3CA4
SCHEMBL31743074 0.74 F11 (0.74) CA12CA9CA1CA3CA4
SCHEMBL30874739 0.74 DAO (0.56) CA12CA9CA1CA3CA4
SCHEMBL252706 0.74 CA12 (0.54) CA12CA9CA1CA3CA4
SCHEMBL8061721 0.74 CA12 (0.54) CA12CA9CA1CA3CA4
SCHEMBL436560 0.74 CA12 (0.74) CA12CA9CA1CA3CA4
SCHEMBL708122 0.74 DAO (0.56) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN claimed
CN-111732573-B Quinolone acid-aminopyrimidine compound and preparation method and application thereof 复旦大学 2022-09-16 CN claimed
CN-111732573-A Quinolone acid-aminopyrimidine compound and preparation method and application thereof 复旦大学 2020-10-02 CN claimed
US-20150157621-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING THE SAME MARIPOSA HEALTH LTD (AU) 2015-06-11 US claimed
US-8980914-B2 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same MARIPOSA HEALTH LIMITED (AU) 2015-03-17 US claimed
US-20100079635-A1 OPTICAL ELEMENT WAFER MODULE, OPTICAL ELEMENT MODULE, METHOD FOR MANUFACTURING OPTICAL ELEMENT MODULE, ELECTRONIC ELEMENT WAFER MODULE, METHOD FOR MANUFACTURING ELECTRONIC ELEMENT MODULE, ELECTRONIC ELEMENT MODULE AND ELECTRONIC INFORMATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2010-04-01 US claimed
CN-1902057-A Optical recording medium and dye MITSUBISHI CHEM CORP (JP) 2007-01-24 CN claimed
US-20060235045-A1 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-10-19 US claimed
US-20060223003-A1 Optical recording medium and dye MITSUBISHI CHEMICAL CORPORATION (JP) 2006-10-05 US claimed
EP-1698478-A1 OPTICAL RECORDING MEDIUM AND DYE Mitsubishi Chemical Corporation (JP) 2006-09-06 EP claimed
EP-1650191-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD OF TREATMENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-04-26 EP claimed
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US claimed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP claimed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US claimed
EP-0785190-A2 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-07-23 EP claimed
EP-0374835-B1 THERMALLY-TRANSFERABLE FLUORESCENT 7-AMINOCARBOSTYRILS EASTMAN KODAK COMPANY (US) 1992-11-11 EP claimed
EP-0374835-A1 Thermally-transferable fluorescent 7-aminocarbostyrils EASTMAN KODAK COMPANY (US) 1990-06-27 EP claimed
US-4891352-A FOR SECURITY PURPOSES EASTMAN KODAK COMPANY (US) 1990-01-02 US claimed
JP-6316167-A None JP disclosed
US-3968119-A OPTICAL BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223003-A1 Optical recording medium and dye CHRM1, CACNA1S, OXER1 CA12 1721/4885CA9 1875/4885CA1 521/4885
US-20060235045-A1 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same ELANE, CFTR, ARG2 CA12 1662/4885CA9 3581/4885CA1 3436/4885
US-20150157621-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING THE SAME ELANE, ARG2, CFTR CA12 1525/4885CA9 3717/4885CA1 3292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.