Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386994 | 0.90 | GAA (0.46) | HSP90AA1GAAKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9382960 | 0.83 | HTT (0.42) | GAAKDM4EHTTSMN1; SMN2RAB9A | |
| SCHEMBL9384958 | 0.82 | HTT (0.37) | GAAKMT2AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL9130823 | 0.81 | SMN1; SMN2 (0.58) | GAAKMT2AKDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9387267 | 0.79 | HTT (0.35) | KDM4EHTTALDH1A1 | |
| SCHEMBL9386029 | 0.78 | NCEH1 (0.42) | ALDH1A1 | |
| SCHEMBL9385711 | 0.77 | MGLL (0.45) | — | |
| SCHEMBL9386760 | 0.76 | KDM4E (0.36) | GAAKMT2AKDM4EHTTHPGD | |
| SCHEMBL10525201 | 0.75 | IL1RN (0.36) | GAAKMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9595033 | 0.71 | NPC1 (0.49) | GAAKMT2AKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326981-B1 | 4-Oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide derivatives, their preparation, medicaments containing them and their preparation | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-11-09 | — | — | EP | disclosed |