Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9385389 | 0.99 | HTR1A (0.46) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| SCHEMBL9385200 | 0.92 | HTR1A (0.45) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9384750 | 0.91 | HTR1A (0.44) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| SCHEMBL9388176 | 0.88 | HTR1A (0.45) | HTR1AHTR2AHRH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9383653 | 0.88 | MAPT (0.48) | HTR1AHTR2AALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9384567 | 0.88 | HTR1A (0.45) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| SCHEMBL9386908 | 0.88 | HTR1A (0.45) | HTR1AHTR2AHRH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9384577 | 0.88 | HTR1A (0.46) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| SCHEMBL9388964 | 0.88 | HTR1A (0.50) | HTR1AHTR2AHRH1HRH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9385657 | 0.87 | MAPT (0.44) | HTR1AHTR2AHRH1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |