Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867464 | 0.76 | ESR1 (0.38) | ALDH1A1ESR1KMT2A | |
| SCHEMBL10914265 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1ESR1NR3C2HSP90AA1 | |
| SCHEMBL9541750 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1ESR1NR3C2HSP90AA1 | |
| SCHEMBL9661401 | 0.73 | S100B (0.53) | TSHRALDH1A1ESR1KMT2AMAPK1 | |
| Diethylaniline SCHEMBL9487131 | 0.72 | ALDH1A1 (0.56) | TSHRALDH1A1GLAESR1KMT2A | |
| SCHEMBL1257089 | 0.71 | TSHR (0.43) | TSHRALDH1A1GLAESR1KMT2A | |
| SCHEMBL5892163 | 0.71 | ESR1 (0.59) | TSHRALDH1A1GLAESR1KMT2A | |
| Sulfuric Acid SCHEMBL8646873 | 0.71 | TSHR (0.48) | TSHRALDH1A1GLAESR1KMT2A | |
| Diethylaniline SCHEMBL27592326 | 0.71 | ALDH1A1 (0.55) | TSHRALDH1A1GLAESR1KMT2A | |
| SCHEMBL6017430 | 0.71 | ESR1 (0.59) | TSHRALDH1A1GLAESR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | claimed |
| CN-113841280-B | Electrolyte composition, solvent composition, nonaqueous electrolyte solution, and use thereof | 株式会社日本触媒 | 2024-08-09 | — | — | CN | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |