Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253858 | 1.00 | ADORA3 (0.81) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL21097446 | 0.91 | ADORA3 (0.71) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL29762124 | 0.90 | ADORA3 (0.83) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL29762727 | 0.90 | ADORA3 (0.83) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL27191647 | 0.86 | TSHR (0.77) | ADORA3TSHRADORA2AADORA2BCYP3A4 | |
| SCHEMBL25167728 | 0.85 | ADORA3 (0.98) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL13987696 | 0.85 | ADORA3 (0.98) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL29974963 | 0.85 | ADORA3 (0.98) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL723530 | 0.85 | ADORA3 (0.98) | ADORA3TSHRTP53SLC29A1TDP1 | |
| SCHEMBL20491589 | 0.85 | ADORA3 (0.78) | ADORA3TSHRTP53SLC29A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601092-A1 | METHOD FOR THE SELECTION OF GENETICALLY TRANSFORMED CELLS AND COMPOUNDS FOR USE IN THE METHOD | Novartis AG (CH) | 1994-06-15 | — | — | EP | claimed |
| WO-1993005163-A1 | METHOD FOR THE SELECTION OF GENETICALLY TRANSFORMED CELLS AND COMPOUNDS FOR USE IN THE METHOD | SANDOZ LTD. (CH) | 1993-03-18 | — | — | WO | claimed |