Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630915 | 0.84 | THRB (0.37) | THRBGAAALDH1A1HTTPLAU | |
| SCHEMBL11117673 | 0.84 | THRB (0.41) | THRBGAAALDH1A1HTTPLAU | |
| SCHEMBL11686946 | 0.84 | LMNA (0.43) | THRBGAAALDH1A1HTTPLAU | |
| SCHEMBL8365502 | 0.84 | CA1 (0.39) | THRBGAAALDH1A1HTTPLAU | |
| SCHEMBL9914993 | 0.77 | TSHR (0.48) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4235972 | 0.75 | GAA (0.42) | THRBGAAALDH1A1HTTPLAU | |
| SCHEMBL8422579 | 0.74 | LMNA (0.61) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7718128 | 0.72 | THRB (0.36) | THRBGAAALDH1A1HTT | |
| SCHEMBL9393514 | 0.72 | LMNA (0.39) | GAAALDH1A1HTTCYP1A2CYP2C19 | |
| SCHEMBL29326030 | 0.71 | THRB (0.39) | THRBGAAALDH1A1HTTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994006781-A1 | NEW COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | INSTITUTE OF CANCER RESEARCH (GB) | 1994-03-31 | — | — | WO | disclosed |