Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384295 | 0.89 | CYP1A2 (0.52) | MAPTCYP1A2CYP2D6POLBBACE1 | |
| SCHEMBL6809200 | 0.85 | CYP1A2 (0.53) | MAPTALDH1A1MAPK1CYP1A2CYP2D6 | |
| SCHEMBL6639628 | 0.85 | CYP1A2 (0.53) | MAPTALDH1A1MAPK1CYP1A2CYP2D6 | |
| SCHEMBL10665624 | 0.85 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL10663985 | 0.83 | CYP1A2 (0.45) | MAPTALDH1A1CYP1A2CYP2D6POLB | |
| SCHEMBL10348526 | 0.82 | MAOB (0.56) | MAPTALDH1A1LMNAMAPK1GAA | |
| SCHEMBL9296378 | 0.82 | MAOB (0.56) | MAPTALDH1A1LMNAMAPK1GAA | |
| SCHEMBL6985307 | 0.81 | SMN1; SMN2 (0.62) | MAPTALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL10666472 | 0.81 | SMN1; SMN2 (0.62) | MAPTALDH1A1LMNAGAACYP1A2 | |
| SCHEMBL1647125 | 0.81 | BACE1 (0.67) | MAPTCYP1A2CYP2D6BACE1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240659-B2 | N-substituted 3,4,5,6-tetrahydrophthalimides and their precursors | BASF AG (DE) | 1994-10-26 | — | — | EP | claimed |
| US-3933834-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3932645-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS | FARBENFABRIKEN BAYER AG (DT) | 1976-01-13 | — | — | US | disclosed |