Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 7/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 6/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL3634178 | 0.88 | CCR2 (0.44) | CCR2RAB9AALDH1A1KDM4E | |
| Acrylic Acid SCHEMBL5336965 | 0.83 | CCR2 (0.44) | CCR2RAB9AALDH1A1KDM4E | |
| 2-Pyrrolidone SCHEMBL500136 | 0.81 | OR51E2 (0.50) | FKBP5CRBNCCR2CTSDOR51E2 | |
| Acetic Acid SCHEMBL28307059 | 0.81 | CCR2 (0.47) | CCR2RAB9AALDH1A1 | |
| Caprolactam SCHEMBL4163313 | 0.79 | CRBN (0.59) | FKBP5CRBNCCR2SIRT2SIRT1 | |
| Caprolactam SCHEMBL2325626 | 0.78 | CRBN (0.61) | FKBP5CRBNCCR2CTSDOR51E2 | |
| 2-Pyrrolidone SCHEMBL868380 | 0.76 | L3MBTL1 (0.35) | FKBP5CRBNCCR2OR51E2 | |
| SCHEMBL29221977 | 0.76 | CCR2 (0.42) | FKBP5CRBNCCR2RAB9AALDH1A1 | |
| SCHEMBL17101670 | 0.76 | CCR2 (0.42) | FKBP5CRBNCCR2RAB9AALDH1A1 | |
| SCHEMBL2549849 | 0.76 | CCR2 (0.42) | FKBP5CRBNCCR2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002540-A1 | HIGHLY FILLED POLYMERIC COMPOSITIONS | LUCEY MICHAEL F (US) | 1994-02-03 | — | — | WO | disclosed |