Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391205 | 0.90 | MCL1 (0.45) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9392943 | 0.87 | LTA4H (0.40) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9390908 | 0.85 | LTA4H (0.39) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9390901 | 0.85 | LTA4H (0.39) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9390865 | 0.85 | SMN1; SMN2 (0.42) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9390873 | 0.82 | OXER1 (0.58) | OXER1FFAR1 | |
| SCHEMBL9394480 | 0.82 | OXER1 (0.56) | OXER1FFAR1 | |
| SCHEMBL9389753 | 0.81 | OXER1 (0.48) | OXER1FFAR1 | |
| SCHEMBL9389793 | 0.81 | SMN1; SMN2 (0.47) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9392205 | 0.80 | CYP2D6 (0.39) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018168-A1 | INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-18 | — | — | WO | disclosed |