Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392943 | 0.96 | LTA4H (0.40) | LTA4HKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9390908 | 0.91 | LTA4H (0.39) | LTA4HCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9391205 | 0.86 | MCL1 (0.45) | LTA4HMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9389762 | 0.85 | LTA4H (0.41) | LTA4HKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9390776 | 0.85 | FFAR1 (0.47) | KDM4EMEN1KMT2AOXER1MTNR1A | |
| SCHEMBL9390873 | 0.79 | OXER1 (0.58) | MEN1KMT2AOXER1FFAR1LMNA | |
| SCHEMBL9394480 | 0.79 | OXER1 (0.56) | OXER1FFAR1LMNA | |
| SCHEMBL9389793 | 0.78 | SMN1; SMN2 (0.47) | LTA4HKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9390865 | 0.77 | SMN1; SMN2 (0.42) | LTA4HKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9391657 | 0.75 | PTGDR2 (0.51) | OXER1FFAR1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026710-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5α-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |