Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.47 |
| ▸ | DDO | Q99489 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352458 | 0.86 | DAO (0.53) | DAODDOKDM4EALDH1A1GLA | |
| SCHEMBL9389319 | 0.81 | GRIN2D (0.56) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL9388916 | 0.74 | KDM4E (0.46) | GSK3BCCNB2CDK1CCNB1GSK3A | |
| SCHEMBL9393064 | 0.74 | DAO (0.36) | DAODDOSRC | |
| SCHEMBL9007836 | 0.73 | METAP2 (0.49) | DAODDOGSK3BCCNB2CDK1 | |
| SCHEMBL9387730 | 0.73 | HPGD (0.60) | DAODDOGSK3BCDK1CCNB1 | |
| SCHEMBL9387604 | 0.73 | DAO (0.55) | DAODDOSRC | |
| SCHEMBL9387738 | 0.73 | DAO (0.65) | DAODDOKDM4EALDH1A1 | |
| SCHEMBL9387632 | 0.73 | DAO (0.65) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL9387925 | 0.73 | DAO (0.53) | DAODDOSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |