Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384540 | 0.86 | KCNH2 (0.40) | ALDH1A1KMT2AKCNH2SLC22A2ADRB1 | |
| SCHEMBL9385398 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KMT2AKCNH2SLC22A2ADRB1 | |
| Oxalic Acid SCHEMBL9389932 | 0.85 | TDP1 (0.41) | ALDH1A1KMT2AKCNH2SLC22A2ADRB1 | |
| SCHEMBL9388850 | 0.78 | KMT2A (0.48) | ALDH1A1KMT2AKCNH2SLC22A2ADRB1 | |
| SCHEMBL9384406 | 0.77 | LMNA (0.61) | ALDH1A1KMT2AMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL9383787 | 0.77 | KMT2A (0.47) | ALDH1A1KMT2AKCNH2SLC22A2ADRB1 | |
| SCHEMBL9385825 | 0.77 | IGF1R (0.58) | ALDH1A1KMT2AKCNH2MEN1MAPT | |
| Hydrochloric Acid SCHEMBL9383884 | 0.76 | IGF1R (0.57) | ALDH1A1KMT2AKCNH2MEN1MAPT | |
| Oxalic Acid SCHEMBL9384506 | 0.75 | LMNA (0.57) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL10492780 | 0.75 | MAPT (0.64) | ALDH1A1KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |