Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 10/20 | 0.43 |
| ▸ | DDO | Q99489 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392688 | 0.84 | DAO (0.41) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9389908 | 0.84 | DAO (0.50) | DAODDOGRIN1GRIN2A | |
| SCHEMBL9389414 | 0.82 | DAO (0.58) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9389943 | 0.80 | DAO (0.42) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9392228 | 0.78 | DAO (0.43) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9390047 | 0.77 | DAO (0.42) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9393136 | 0.76 | DAO (0.43) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9389032 | 0.74 | DAO (0.48) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9389830 | 0.74 | DAO (0.68) | DAODDOMAPTGRIN1GRIN2A | |
| SCHEMBL9393239 | 0.74 | DAO (0.48) | DAODDOGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |