Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390169 | 1.00 | SRD5A1 (0.44) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9390163 | 1.00 | SRD5A1 (0.44) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6757166 | 0.92 | CNR2 (0.44) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6757165 | 0.92 | CNR2 (0.44) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6757164 | 0.92 | CNR2 (0.44) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9392186 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL9392179 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL9392187 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNARAB9ANPC1KDM4E | |
| SCHEMBL7571151 | 0.84 | CYP11B2 (0.44) | CYP19A1CYP11B1CYP11B2RAB9ANPC1 | |
| SCHEMBL7571157 | 0.84 | CYP11B2 (0.44) | CYP19A1CYP11B1CYP11B2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | claimed |
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | disclosed |