Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.53 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391078 | 1.00 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19GAAL3MBTL1 | |
| SCHEMBL9391013 | 0.89 | KDM4E (0.59) | CYP1A2CYP2D6CYP2C19GAAPLAAT3 | |
| SCHEMBL9391023 | 0.89 | KDM4E (0.59) | CYP1A2CYP2D6CYP2C19GAAPLAAT3 | |
| SCHEMBL9395867 | 0.87 | KDM4E (0.46) | CYP1A2CYP2D6CYP2C19GAAL3MBTL1 | |
| SCHEMBL9395775 | 0.87 | PLAAT3 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL9395784 | 0.87 | PLAAT3 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4CNR1 | |
| SCHEMBL9395862 | 0.87 | KDM4E (0.46) | CYP1A2CYP2D6CYP2C19GAAL3MBTL1 | |
| SCHEMBL9392501 | 0.86 | PLAAT3 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4MAPT | |
| SCHEMBL9392511 | 0.86 | PLAAT3 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4MAPT | |
| SCHEMBL9392384 | 0.84 | SMN1; SMN2 (0.61) | GAAPLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |