Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392391 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9391023 | 0.86 | KDM4E (0.59) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9391013 | 0.86 | KDM4E (0.59) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9395784 | 0.85 | PLAAT3 (0.55) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9395867 | 0.85 | KDM4E (0.46) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9395862 | 0.85 | KDM4E (0.46) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9395775 | 0.85 | PLAAT3 (0.55) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9391078 | 0.84 | CYP1A2 (0.58) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9391085 | 0.84 | CYP1A2 (0.58) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9392501 | 0.84 | PLAAT3 (0.53) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |