Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | AGER | Q15109 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728633 | 1.00 | KDM4E (0.74) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Quinolinic Acid SCHEMBL27725715 | 0.88 | KDM4E (0.88) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL31513532 | 0.88 | PARP1 (0.58) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL773980 | 0.88 | PARP1 (0.58) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Quinolinic Acid SCHEMBL69230 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Quinolinic Acid SCHEMBL29356188 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Quinolinic Acid SCHEMBL343618 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| Quinolinic Acid SCHEMBL27676801 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL5158054 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL6333183 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1MAPTALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997207-A | A kind of synthetic method of 2-aminopyridine -3- carboxylic acid | 江苏师范大学 | 2018-12-14 | — | — | CN | claimed |
| CN-101959863-B | Process for production of 3-amino-2-chloro-6- trifluoromethylpyridine | ISHIHARA SANGYO KAISHA | 2014-01-08 | — | — | CN | claimed |
| EP-2376472-A1 | PROCESS FOR MANUFACTURING 5-FORMYL-PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS | BASF SE (DE) | 2011-10-19 | — | — | EP | claimed |
| WO-2010066668-A1 | PROCESS FOR MANUFACTURING 5-FORMYL-PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS | BASF SE (DE) | 2010-06-17 | — | — | WO | claimed |
| CN-114790167-B | Preparation method of 2, 3-dichloropyridine | 北京弗莱明科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114761016-A | Antiviral heterocyclic compounds | 英安塔制药有限公司 | 2022-07-15 | — | — | CN | disclosed |
| EP-1991651-B2 | SURFACE ACTIVE BLEACH AT DYNAMIC PH | PROCTER & GAMBLE (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-108587994-B | Engineering bacterium with cyclic imide hydrolase activity D-hydantoinase, and construction method, culture method and application thereof | 山西大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114057635-A | 2-aryl ureido-N- [2- (2-methoxyphenoxy) ethyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-113979935-A | 2-aryl ureido-N- (4-fluorobenzyl) nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113979936-A | 2-aryl ureido-N- [3- (4-morpholinyl) propyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-112494476-A | Use of compounds for the treatment of obesity | 新德发制药有限公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-0278944-A1 | Substituted 2,6-substituted pyridine compounds | Monsanto Company (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0259687-A2 | Method for the preparation of pyridine-2,3-dicarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0254951-A2 | 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1988-02-03 | — | — | EP | disclosed |
| EP-0184027-A2 | Preparation of substituted and unsubstituted 2-carbamoyl nicotinic and 3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1986-06-11 | — | — | EP | disclosed |
| US-4443355-A | CELLULASE PRODUCED BY CELLULOMONAS | KAO CORPORATION (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| US-3947442-A | Method for producing heterocyclic acid anhydrides and pyrimidinediones | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3947416-A | Azaisatoic anhydrides | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |