Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391965 | 1.00 | ATM (0.39) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9395262 | 0.93 | ATM (0.36) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9395264 | 0.93 | ATM (0.36) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9212597 | 0.93 | ATM (0.41) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9212594 | 0.93 | ATM (0.41) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9392709 | 0.91 | ATM (0.40) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9392710 | 0.91 | ATM (0.40) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL1119086 | 0.82 | ATM (0.39) | ATMSMN1; SMN2MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL3834729 | 0.81 | ATM (0.38) | ATMSMN1; SMN2POLBOPRM1ALDH1A1 | |
| Acetic Acid SCHEMBL9774420 | 0.78 | ALDH1A1 (0.37) | ATMSMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994017069-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1994-08-04 | — | — | WO | disclosed |