Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392506 | 1.00 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTTAAR1KMT2A | |
| SCHEMBL12717314 | 0.77 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2MAPTTAAR1HPGD | |
| SCHEMBL9391023 | 0.74 | KDM4E (0.59) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL6318345 | 0.74 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPTTAAR1KMT2A | |
| SCHEMBL9391013 | 0.74 | KDM4E (0.59) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL7783342 | 0.74 | EPHX1 (0.73) | ALDH1A1SMN1; SMN2MAPTTAAR1KMT2A | |
| SCHEMBL9395784 | 0.73 | PLAAT3 (0.55) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 | |
| SCHEMBL9395867 | 0.73 | KDM4E (0.46) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL9395862 | 0.73 | KDM4E (0.46) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL9395775 | 0.73 | PLAAT3 (0.55) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |