SCHEMBL939422

SCHEMBL939422

CCN=C=NC(C)CN(C)C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL332797 0.98 CYP1A2 (0.39) CYP1A2CYP2D6
Methyl Alcohol SCHEMBL28396245 0.94 CYP1A2 (0.37) CYP1A2CYP2D6
SCHEMBL287060 0.77
SCHEMBL3832949 0.76 CYP1A2 (0.53) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL6806460 0.75 CYP1A2 (0.52) CYP1A2CYP2D6
SCHEMBL28210729 0.73 TRPA1 (0.36) CYP1A2CYP2D6
SCHEMBL6443991 0.73 CYP1A2 (0.39) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL28210727 0.71 TRPA1 (0.34)
Hydrochloric Acid SCHEMBL8537869 0.71 CYP1A2 (0.38) CYP1A2CYP2D6
SCHEMBL7484113 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925407-A Liver-targeted modified lipid derivative and pharmaceutical formulation containing same 苏州核鼎生物技术有限公司 2020-11-13 CN claimed
CN-102336802-B Glycyrrhetinic acid-modified lipid, liver targeting liposome, micelle and compound, and their preparation method UNIV SICHUAN 2013-11-06 CN claimed
CN-102336802-A Glycyrrhetinic acid-modified lipid, liver targeting liposome, micelle and compound, and their preparation method UNIV SICHUAN 2012-02-01 CN claimed
CN-101757642-A Method for preparing gadolinium-containing nano particles UNIV TIANJIN SCIENCE & TECH 2010-06-30 CN claimed
CN-100428960-C Method for preparing nano liver-target biodegradating medicine carrier material UNIV NANKAI (CN) 2008-10-29 CN claimed
CN-1743008-A Method for preparing nano liver-target biodegradating medicine carrier material UNIV NANKAI (CN) 2006-03-08 CN claimed
CN-111925407-A Liver-targeted modified lipid derivative and pharmaceutical formulation containing same 苏州核鼎生物技术有限公司 2020-11-13 CN disclosed
EP-3075395-B1 POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF Bayer Pharma AG (DE) 2017-11-22 EP disclosed
EP-3075395-A1 POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF Bayer Pharma Aktiengesellschaft (DE) 2016-10-05 EP disclosed
CN-103998063-B Polyethylene glycol based prodrugs of adrenomedullin and uses thereof 拜耳制药股份公司 2016-09-21 CN disclosed
CN-105849109-A Substituted oxopyridine derivatives 拜耳制药股份公司 2016-08-10 CN disclosed
EP-2773376-B1 POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF Bayer Pharma AG (DE) 2016-01-13 EP disclosed
CN-102336802-B Glycyrrhetinic acid-modified lipid, liver targeting liposome, micelle and compound, and their preparation method UNIV SICHUAN 2013-11-06 CN disclosed
US-5594091-A POLYLACTONES FOR MICROCAPSULES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-14 US disclosed
EP-0668073-A2 Polyester matrix for a pharmaceutical sustained-release preparation TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-08-23 EP disclosed
EP-0344519-B1 SUBSTITUTED 4-(QUINOLIN-2-YL-METHOXY)PHENYL-ACETIC-ACID DERIVATIVES BAYER AG (DE) 1993-04-14 EP disclosed
EP-0477717-A2 New 3-substituted cephalosporins, process for their preparation and their use as medicinal preparations BAYER AG (DE) 1992-04-01 EP disclosed
EP-0242518-B1 Cycloalkano[1,2-b]indole-sulfonamides BAYER AG (DE) 1991-04-10 EP disclosed
EP-0412350-A2 Renininhibitors, procedure for their preparation and use as medicaments BAYER AG (DE) 1991-02-13 EP disclosed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 EP disclosed