Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | EYA2 | O00167 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644210 | 0.93 | TDP1 (0.52) | TDP1EYA2APPACEBLM | |
| SCHEMBL27164808 | 0.90 | BLM (0.52) | TDP1EYA2APPACEBLM | |
| SCHEMBL9642177 | 0.85 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| SCHEMBL15831761 | 0.83 | BLM (0.62) | TDP1EYA2APPACEBLM | |
| SCHEMBL8441603 | 0.83 | TDP1 (0.58) | TDP1EYA2APPACEBLM | |
| SCHEMBL2808370 | 0.83 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| SCHEMBL1273738 | 0.83 | TDP1 (0.56) | TDP1EYA2APPACEBLM | |
| SCHEMBL31040408 | 0.82 | LMNA (0.52) | BLMLMNAALOX15SLC6A2SLC6A3 | |
| SCHEMBL31040447 | 0.82 | LMNA (0.52) | BLMLMNAALOX15SLC6A2SLC6A3 | |
| SCHEMBL26602930 | 0.79 | SLC6A5 (0.41) | TDP1BLMLMNAALOX15SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345723-B1 | Diethylenetriamine pentaacetic acid derivatives | NIHON MEDIPHYSICS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5250702-A | Nonradioactive carriers for radioactive metal elements | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5094950-A | Diagnostics | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |