Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452487 | 1.00 | CYP3A4 (0.60) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL54044 | 1.00 | CYP3A4 (0.60) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL11328600 | 0.85 | MMP2 (0.45) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| Benzofuran SCHEMBL5614200 | 0.84 | CYP3A4 (0.49) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL11317507 | 0.84 | CYP3A4 (0.44) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL11314461 | 0.81 | MMP2 (0.47) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL10311721 | 0.80 | ADAMTS4 (0.48) | MMP2ADAMTS4ADAMTS5SSTR4MMP3 | |
| SCHEMBL11326660 | 0.79 | MMP2 (0.46) | CYP3A4MMP2ADAMTS4ADAMTS5SSTR4 | |
| SCHEMBL11303236 | 0.79 | CYP3A4 (0.52) | CYP3A4MMP2KMT2A | |
| SCHEMBL12310940 | 0.78 | MMP2 (0.45) | MMP2ADAMTS4ADAMTS5SSTR4MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6145012-A | — | — | None | — | — | JP | disclosed |
| JP-H06145012-A | HERBICIDE CONTAINING OXAZOLONE DERIVATIVE, BROMOBUTIDE AND THE LIKE | SANKYO CO LTD | 1994-05-24 | — | — | JP | disclosed |