Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 11/20 | 1.00 |
| ▸ | GRIA2 | P42262 | 10/20 | 1.00 |
| ▸ | GRIA4 | P48058 | 10/20 | 1.00 |
| ▸ | GRIK5 | Q16478 | 10/20 | 1.00 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393484 | 1.00 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5KMO | |
| SCHEMBL9393490 | 1.00 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5KMO | |
| SCHEMBL9395817 | 0.85 | GRIA1 (0.74) | GRIA1GRIA2GRIA4GRIK5KMO | |
| SCHEMBL13227277 | 0.74 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL9540945 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA4GRIK5KMT2A | |
| SCHEMBL11300643 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL9393535 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL13227276 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL9393529 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5CYP1A2 | |
| SCHEMBL8296645 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022841-A1 | ALKYLAMINO SUBSTITUTED TRIAZINEDIONES, TRIAZINEMONOTHIONES AND TRIAZINEDITHIONES | TOCRIS COOKSON LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |