Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | WRN | Q14191 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304991 | 0.86 | GRIA1 (0.54) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL11407099 | 0.74 | NPSR1 (0.47) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL11402130 | 0.73 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL9540945 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL9393490 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL9393484 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL9396137 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL11403127 | 0.71 | ALDH1A1 (0.46) | GRIA1GRIA2GRIA4GRIK5ALDH1A1 | |
| SCHEMBL24599140 | 0.71 | GRIA1 (0.44) | GRIA1GRIA2GRIA4GRIK5HIF1A | |
| SCHEMBL6268666 | 0.69 | PDE3A (0.47) | GRIA1GRIA2GRIA4GRIK5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56083480-A | — | — | None | — | — | JP | disclosed |
| US-4297129-A | HERBICIDES; WILD OATS; NONPHYTOTOXIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-27 | — | — | US | disclosed |
| JP-S5683480-A | 2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING THE SAME AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1981-07-08 | — | — | JP | disclosed |