Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388054 | 0.97 | KDM4E (0.51) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL15858102 | 0.94 | KDM4E (0.61) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL2890076 | 0.92 | PKM (0.47) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7383587 | 0.91 | KDM4E (0.57) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL6232755 | 0.89 | MEN1 (0.49) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL18748417 | 0.88 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL26032283 | 0.85 | CA12 (0.56) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL22469882 | 0.85 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL31568470 | 0.85 | KDM4E (0.55) | KDM4EHSD17B10MAPTLMNAALDH1A1 | |
| SCHEMBL20894429 | 0.84 | KDM4E (0.47) | KDM4EHSD17B10MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026695-A1 | NOVEL LUPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1994-11-24 | — | — | WO | disclosed |