SCHEMBL6232755

SCHEMBL6232755

CC(C)(C)OC(=O)Nc1cc(NC(=O)OC(C)(C)C)cc(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
POLB P06746 2/20 0.44
MAPT P10636 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
PKM P14618 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP17A1 P05093 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
NAMPT P43490 1/20 0.43
TOP2A P11388 1/20 0.42
TOP2B Q02880 1/20 0.42
P2RY14 Q15391 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890076 0.96 PKM (0.47) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL7388054 0.92 KDM4E (0.51) MEN1KMT2AMAPTHDAC3HDAC1
SCHEMBL2178704 0.90 CA12 (0.46) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL25923116 0.90 TPMT (0.48) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL14655623 0.89 MEN1 (0.45) MEN1KMT2APOLBMAPTHDAC3
Hydrochloric Acid SCHEMBL7387613 0.89 MEN1 (0.42) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL5219158 0.89 HDAC3 (0.43) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL29032844 0.89 L3MBTL1 (0.46) MEN1KMT2AMAPTHDAC3HDAC1
SCHEMBL4726163 0.89 EPHX2 (0.42) MEN1KMT2APOLBMAPTHDAC3
SCHEMBL30569642 0.89 L3MBTL1 (0.46) MEN1KMT2AMAPTHDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359185-B Preparation method of high-capacity carbon composite graphene anode material 深圳鑫茂新能源技术股份有限公司 2024-08-27 CN claimed
CN-118359185-A Preparation method of high-capacity carbon composite graphene anode material 深圳鑫茂新能源技术股份有限公司 2024-07-19 CN claimed
CN-117209887-B High-toughness durable polypropylene material and preparation process thereof 珠海市金塑塑料有限公司 2024-04-16 CN claimed
CN-117209887-A High-toughness durable polypropylene material and preparation process thereof 广东科净塑料制品有限公司 2023-12-12 CN claimed
CN-119930516-A Peptide urea derivative, pharmaceutical composition containing same and application of peptide urea derivative 晶核生物医药科技(南京)有限公司 2025-05-06 CN disclosed
CN-116514735-B Peptide urea derivative, pharmaceutical composition containing same and application of peptide urea derivative 晶核生物医药科技(南京)有限公司 2025-02-28 CN disclosed
CN-118359185-B Preparation method of high-capacity carbon composite graphene anode material 深圳鑫茂新能源技术股份有限公司 2024-08-27 CN disclosed
CN-118359185-A Preparation method of high-capacity carbon composite graphene anode material 深圳鑫茂新能源技术股份有限公司 2024-07-19 CN disclosed
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF CHENGDU SINTANOVO BIOTECHNOLOGY CO., LTD. (CN) 2024-05-16 US disclosed
CN-117209887-B High-toughness durable polypropylene material and preparation process thereof 珠海市金塑塑料有限公司 2024-04-16 CN disclosed
CN-114805487-B Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2024-03-12 CN disclosed
EP-4321525-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Chengdu Sintanovo Biotechnology Co., Ltd (CN) 2024-02-14 EP disclosed
US-20030113265-A1 Bile acids conjugates with metal ion chelates and the use thereof BRACCO IMAGING S.P.A. (IT) 2003-06-19 US disclosed
EP-1259532-A1 BILE ACIDS CONJUGATES WITH METAL ION CHELATES AND THE USE THEREOF Bracco Imaging S.p.A. (IT) 2002-11-27 EP disclosed
US-6316491-B1 INHIBITORS OF TYROSINE KINASE USED AS ANTITUMOR OR IMMUNOSUPPRESSION AGENTS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-11-13 US disclosed
US-20010027208-A1 Radicicol derivatives INO YOJI (JP) 2001-10-04 US disclosed
WO-2001064708-A1 BILE ACIDS CONJUGATES WITH METAL ION CHELATES AND THE USE THEREOF BRACCO IMAGING S.P.A. (IT) 2001-09-07 WO disclosed
US-6239168-B1 ANTITUMOR AGENTS, IMMUNOSUPPRESSANTS; TYROSINE KINASE INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-05-29 US disclosed
EP-0889042-A1 RADICICOL DERIVATIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 1999-01-07 EP disclosed
US-5310916-A Trifunctional agents useful as irreversible inhibitors of A1-adenosine receptors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF GHSR, GHRHR, GIPR MEN1 533/4885KMT2A 2823/4885POLB 4780/4885
US-20030113265-A1 Bile acids conjugates with metal ion chelates and the use thereof SLC10A2, SLC10A1, NR1H4 MEN1 168/4885KMT2A 3139/4885POLB 3623/4885
US-20010027208-A1 Radicicol derivatives ROS1, LYN, SRC MEN1 3868/4885KMT2A 3759/4885POLB 3221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.